Manchester City are into the Champions League quarter-finals for the first time in their history thanks to a 3-1 aggregate victory over Dynamo Kiev, but it came at a heavy cost as they lost Vincent Kompany to yet another injury.Man City 0-0 Dynamo Kiev Read our match report as City booked their place in the Champions League quarter-finals. Less than five minutes had passed at the Etihad Stadium when the City skipper pulled up and immediately gestured to the bench before trudging down the tunnel to be replaced by Eliaquim Mangala.Manuel Pellegrini confirmed Kompany will miss at least a month with a recurrence of the calf problem that has troubled him throughout the season. It rules him out of a string of crucial games for City, starting with their Super Sunday showdown against Manchester United, live on Sky Sports. Citys defensive problems were compounded as Nicolas Otamendi was also forced off later in the first half, but it is the loss of Kompany that will cause the most concern as they enter the final two months of the season. The Belgian has been sidelined for 27 of Citys 46 games in all competitions this season due to persistent calf problems, and he has been sorely missed, with the likes of Mangala and Martin Demichelis struggling in his absence. Man City with and without Vincent Kompany starting - PL 2015/16 With Kompany Premier League 2015/16 Without Kompany 13 Games 16 8 Wins 7 3 Draws 3 2 Losses 6 61.54% Win % 43.75% 6 Goals conceded 25 194 Mins per goal conceded 65 9 Clean sheets 4 Statistics highlight his importance to the side. Citys Premier League win percentage with Kompany starting this season is 61.54 per cent compared to 43.75 per cent without him, and their defensive record is also far better with the Belgian starting.City have kept nine clean sheets in the 13 games he has started and just four in 16 he has missed, and they have averaged just 0.46 goals conceded with him compared 1.56 without him. Vincent Kompany has been troubled by a calf problem throughout the campaign It all adds up to a major headache for Pellegrini. Mangala and Demichelis didnt have too many problems dealing with the minimal threat of Dynamo Kiev, but there are far tougher games ahead, and the City boss will be all too aware of the potential repercussions of losing Kompany.Citys Premier League title hopes are already hanging by a thread, and a failure to win Sundays Manchester derby could leave them sweating on a top-four finish. Without their leader, the challenges ahead look considerably harder. 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The Longhorns (14-4, 3-2) got their biggest win of the season with their third in the row in the Big 12.ATLANTA -- John Isner opened his bid for a fourth straight BB&T Atlanta Open title Wednesday night, overpowering Frances Adrian Mannarino 6-4, 6-0.I dont know if Ive ever won 10 games in a row, but Ill take it, Isner said.The 6-foot-10 former University of Georgia star has reached the finals in Atlanta five of the previous six years and is 21-3 in the event. He has 10 ATP Tour titles.I think tactically I did some things well out there. I needed to go to his forehand and I did. I was going to his backhand a little too much early on and was paying the price for it. The game plan was get the ball high and up on his forehand becausee he does not like that at all.ddddddddddddIn the quarterfinals, Isner will face face eighth-seeded Taylor Fritz in an all-American match. Fritz topped American Bjorn Fratangelo 4-6, 6-4, 6-2 in the late match.Seventh-seeded Donald Young and fellow American Reilly Opelka set up a quarterfinal matchup in the afternoon session. Young beat countryman Tim Smyczek 4-6, 7-6 (1), 6-3, and 18-year-old Opelka upset third-seeded Kevin Anderson of South Africa,6-7 (5), 6-3, 7-5. The 6-foot-11 Opelka had 20 aces. ' ' '